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What is Bipolar Disorder?
According to the NIMH
Bipolar disorder (formerly called manic-depressive illness or manic depression) is a mental disorder that causes unusual shifts in mood, energy, activity levels, concentration, and the ability to carry out day-to-day tasks.
Depression and Bipolar Support Alliance
Bipolar disorder is more likely to affect the children of parents who have the disorder. When one parent has bipolar disorder, the risk to each child is l5 to 30%. When both parents have bipolar disorder, the risk increases to 50 to 75%. (National Institute of Mental Health)
Bipolar Disorder may be at least as common among youth as among adults. In a recent NIMH study, one percent of adolescents ages 14 to 18 were found to have met criteria for bipolar disorder or cyclothymia in their lifetime. (National Institute of Mental Health)
Some 20% of adolescents with major depression develop bipolar disorder within five years of the onset of depression. (Birmaher, B., “Childhood and Adolescent Depression: A Review of the Past 10 Years.” Part I, 1995)
Up to one-third of the 3.4 million children and adolescents with depression in the United States may actually be experiencing the early onset of bipolar disorder. (American Academy of Child and Adolescent Psychiatry, 1997)
When manic, children and adolescents, in contrast to adults, are more likely to be irritable and prone to destructive outbursts than to be elated or euphoric. When depressed, there may be many physical complaints such as headaches, and stomachaches or tiredness; poor performance in school, irritability, social isolation, and extreme sensitivity to rejection or failure. (National Institute of Mental Health).
Tell Me About Bipolar Disorder
ARTICLES ABOUT BIPOLAR DISORDER
The brain uses a number of chemicals as messengers to communicate with other parts of the brain and nervous system. These chemical messengers, known as neurotransmitters, are essential to all of the brain's functions. Since they are messengers, they typically come from one place and go to another to deliver their messages. Where one neuron or nerve cell ends, another one begins. In between two linked neurons is a tiny space or gap called a synapse. In a simple scenario, one cell sends a neurotransmitter message across this synaptic junction and the next cell receives the signal by catching the messenger chemical as it floats across the synapse in a receptor structure. The receiving neuron's capture of the neurotransmitter chemicals alerts it that a message has been sent, and this neuron in turn sends a new message off to additional neurons that it is connected to, and so on down the line.
Importantly, neurons cannot communicate with each other except by means of this synaptic chemical message. The brain would cease to function in an instant if chemical messengers were somehow removed. By providing a mechanism for allowing neurons to communicate with one another, neurotransmitters literally enable the brain to function. There are millions and millions of individual synapses in the brain. The neurotransmitter traffic and activity occurring inside those synapses is constant and complicated.
There are many different kinds of neurotransmitter chemicals in the brain. The neurotransmitters that are implicated in bipolar illness include dopamine, norepinephrine, serotonin, GABA (gamma-aminobutyrate), glutamate, and acetylcholine. Researchers also suspect that another class of neurotransmitter chemicals known as neuropeptides (including endorphins, somatostatin, vasopressin, and oxytocin) play an important role in both normal and bipolar brains.
Measuring neurotransmitters, their chemical variants, locations, and their effects constitute a large area of study in bipolar research. It is known that these chemicals are in some way unbalanced in the bipolar brain compared to normal brain. For example, GABA is observed to be lower in the blood and spinal fluid of bipolar patients, while oxytocin-active neurons are increased in bipolar patients, but the relevancy of these findings to overall brain functioning in bipolar and normal individuals is not yet understood. Whether the presence, absence, or change in these chemicals is a cause or outcome of bipolar disorder remains to be determined, but the importance of neurochemicals in creating bipolar disease is indisputable.
HOW DOES TREATMENT HELP?
month of march
What is ADHD/ADD?
According to the WebMD
ADHD is a chronic condition marked by persistent inattention, hyperactivity, and sometimes impulsivity. ADHD begins in childhood and often lasts into adulthood. As many as 2 out of every 3 children with ADHD continue to have symptoms as adults.
ADDITUDE: Inside the ADHD Mind
In its 2016 study, the CDC found that 3.3 million adolescents ages 12-17 have ever been diagnosed with ADHD.
Teens drivers diagnosed with ADHD are more likely to be in a traffic accident, be issued traffic and moving violations, and engage in risky driving behaviors.14
Up to 27 percent of adolescents with substance abuse disorder have comorbid ADHD.15
Adolescents with ADHD clash with their parents about more issues than do adolescents without ADHD.16
Male high-school students with ADHD are more likely to experience problems with attendance, GPA, homework, and more. Male teens with ADHD miss school 3 to 10 percent of the time; are between 2.7 and 8.1 times more likely to drop out of high school; fail 7.5 percent of their courses; and have GPAs five to nine points lower than those of male teens without ADHD.17
Attention deficit hyperactivity disorder (ADHD/ADD) - causes, symptoms & pathology
ARTICLES ABOUT ADHD / ADD
ADHD / ADD
How Neurotransmitters Work In ADHD Brains
Before I tell you about these special brain chemicals, let me explain a bit about brain anatomy.
There are millions of cells, or neurons, densely packed into various regions of the brain. Each region is responsible for a particular function. Some regions interact with our outside world, interpreting vision, hearing, and other sensory inputs to help us figure out what to do and say. Other regions interact with our internal world — our body — in order to regulate the function of our organs.
For the various regions to do their jobs, they must be linked to one another with extensive “wiring.” Of course, there aren’t really wires in the brain. Rather, there are myriad “pathways,” or neural circuits, that carry information from one brain region to another.
Information is transmitted along these pathways via the action of neurotransmitters (scientists have identified 50 different ones, and there may be as many as 200). Each neuron produces tiny quantities of a specific neurotransmitter, which is released into the microscopic space that exists between neurons (called a synapse), stimulating the next cell in the pathway — and no others.
How does a specific neurotransmitter know precisely which neuron to attach to, when there are so many other neurons nearby? Each neurotransmitter has a unique molecular structure — a “key,” if you will — that is able to attach only to a neuron with the corresponding receptor site, or “lock.” When the key finds the neuron bearing the right lock, the neurotransmitter binds to and stimulates that neuron.
Neurotransmitter Deficiencies In ADHD Brains
Brain scientists have found that deficiencies in specific neurotransmitters underlie many common disorders, including anxiety, mood disorders, anger-control problems, and obsessive-compulsive disorder.
ADHD was the first disorder found to be the result of a deficiency of a specific neurotransmitter — in this case, norepinephrine — and the first disorder found to respond to medications to correct this underlying deficiency. Like all neurotransmitters, norepinephrine is synthesized within the brain. The basic building block of each norepinephrine molecule is dopa; this tiny molecule is converted into dopamine, which, in turn, is converted into norepinephrine.
A Four-Way Partnership
ADHD seems to involve impaired neurotransmitter activity in four functional regions of the brain:
Frontal cortex. This region orchestrates high-level functioning: maintaining attention, organization, and executive function. A deficiency of norepinephrine within this brain region might cause inattention, problems with organization, and/or impaired executive functioning.
Limbic system. This region, located deeper in the brain, regulates our emotions. A deficiency in this region might result in restlessness, inattention, or emotional volatility.
Basal ganglia. These neural circuits regulate communication within the brain. Information from all regions of the brain enters the basal ganglia, and is then relayed to the correct sites in the brain. A deficiency in the basal ganglia can cause information to “short-circuit,” resulting in inattention or impulsivity.
Reticular activating system. This is the major relay system among the many pathways that enter and leave the brain. A deficiency in the RAS can cause inattention, impulsivity, or hyperactivity.
These four regions interact with one another, so a deficiency in one region may cause a problem in one or more of the other regions. ADHD may be the result of problems in one or more of these regions.
HOW DOES TREATMENT HELP?
The symptoms of ADHD (also known as ADD) don’t just impact learning. They can also create difficulties in everyday life with friends and family.
So how is ADHD treated? There are a number of treatments available for ADHD, in addition to medication. Some kids respond best to one kind of treatment. Other kids may do best with a different treatment or combination of treatments. Together with your child’s doctor, you can come up with an ADHD treatment plan that’s tailored to meet your child’s needs.
For many kids, medication is key to ADHD management. Experts largely agree that it’s the most effective form of treatment for most kids with ADHD. Medication works well for around 80 percent of the kids who take it, if the type and dosage is carefully tailored to them. But medication may not be right for all kids and families.
For some kids, ADHD medications can have side effects. These usually go away after a few days. If not, the prescriber will probably suggest trying a different medication to see if that will work better. Or she might recommend changing from a stimulant to a non-stimulant, or vice versa.
It’s fairly common for kids with ADHD to also have anxiety or